Product Name :
STING Recombinant Rabbit Monoclonal Antibody [JM03-47]
Predicted band size :
42 kDa
Observed band size :
35 kDa
Synonyms:
endoplasmic reticulum IFN stimulator antibody Endoplasmic reticulum interferon stimulator antibody ERIS antibody FLJ38577 antibody hMITA antibody hSTING antibody Mediator of IRF3 activation antibody MITA antibody Mitochondrial mediator of IRF3 activation antibody MPYS antibody 展开
Function :
Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.Formula of 879883-54-2 May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within human STING aa 117-379.Tributyl(1-ethoxyethenyl)stannane site
Species reactivity:
Human, Rat
Verify application:
WB, IHC-P, IF-Cell, FC, IF-Tissue, IP
Coupling :
unconjugated
Clone number:
JM03-47
RRID:
AB_3070597
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃.PMID:33593264 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 42 kDa
Positive control :
THP-1 cell lysate, SW620 cell lysate, human lung tissue lysate, THP-1, human tonsil tissue, rat lung tissue.