Product Name :
UTF1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
hUTF 1 antibody hUTF1 antibody Undifferentiated embryonic cell transcription factor 1 antibody UTF 1 antibody UTF1 antibody UTF1_HUMAN antibody
Function :
Undifferentiated embryonic cell transcription factor 1 (UTF1) is expressed in cells of the inner cell mass and the epiblast. Upon activation by Oct-3/4, UTF1 may be responsible for the rapid proliferation and tumorigenic properties of embryonic stem cells. Sox2 is also part of the Oct-3/4-containing complex able to bind the regulatory region of UTF1. UTF1 acts as a transcriptional coactivator of ATF2 and it binds to the N-terminal region of ATF2. Reduced expression in embryonic stem cells (ESCs) is associated with failure to differentiate properly, although self-renewal is unaffected.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide corresponding to Human UTF1 aa 41-90 / 341.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
AB_3073214
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.SulfoxFluor site Aliquot store at -20℃ or -80℃.2-Chloro-4-methylpyrimidin-5-amine supplier Avoid repeated freeze / thaw cycles.PMID:33691558
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 36 kDa
Positive control :
Human brain, D3, human testis