Product Name :
RBM3 Recombinant Rabbit Monoclonal Antibody [JE63-84]
Predicted band size :
Observed band size :
Synonyms:
2600016C11Rik antibody IS1 RNPL antibody MGC105811 antibody MGC118410 antibody OTTHUMP00000025800 antibody OTTHUMP00000025802 antibody OTTMUSP00000019634 antibody OTTMUSP00000019635 antibody OTTMUSP00000019636 antibody Putative RNA binding protein 3 antibody 展开
Function :
Putative RNA-binding protein 3 is a protein that in humans is encoded by the RBM3 gene. This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. RBM3 is cold-induced RNA binding protein and is involved in mRNA biogenesis exerts anti-apoptotic effects. According to antibody-based profiling and transcriptomics analysis, RBM3 protein is present in all analysed human tissues and based on confocal microscopy mainly localised to the nucleoplasm.5-Chloro-2-tetralone site RBM3 is a proto-oncogene that is associated with tumor progression and metastasis and is a potential cancer biomarker.Buy1360774-41-9 Based on patient survival data, high levels of RBM3 protein in tumor cells is a favourable prognostic biomarker in colorectal cancer.PMID:33687655
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within human RBM3 aa 58-157/157.
Species reactivity:
Mouse, Human, Rat
Verify application:
IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
JE63-84
RRID:
AB_3072254
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 17 kDa
Positive control :
Hela, human esophagus tissue, mouse thyroid tissue, mouse trachea tissue, rat trachea tissue, rat esophagus tissue, THP-1.